Oxervate Treatment for Neurotrophic Keratitis

OXERVATE is the first FDA-approved treatment designed for individuals with neurotrophic keratitis, a condition that significantly impacts corneal health. Its primary ingredient, cenegermin, is a recombinant form of human nerve growth factor, which is structurally identical to the nerve growth factor naturally produced by the eyes.

Nerve growth factor plays a crucial role in maintaining corneal health by supporting the nerves associated with this tissue.1,4 In your eyes, the naturally occurring nerve growth factor is believed to: 

- Foster the healing of cells on the corneal surface 

- Help promote tear secretion 

- Improve the function of nerves within the cornea 

Scientific studies have also indicated that nerve growth factor is vital for the survival of corneal epithelial cells and corneal nerves, which is particularly important in conditions like neurotrophic keratitis.2,3,5